10 Best Diet Pills for Weight Loss (That Really Work)

The body positivity movement continues strong momentum with celebritieslike Chrissy Teigen, Mindy Kaling, and Jameela Jamil sharing their personal weight struggles on social media and endorsing people of all shapes and sizes. However, this “love yourself” trend has not stopped Americans from spending nearly $2.1 billion every year on weight-loss dietary supplements in pill form.

I don’t entirely blame them. I’ve struggled with weight issues for many years and know how difficult it is to win the battle of the bulge. And considering how the US has the highest obesity rate worldwide, I’m not alone in this situation. 48 percent of the citizens attribute obesity to poor exercise and diet rather than environmental, social, and genetic factors.

Millennials, especially, are wary of unhealthy lifestyles with almost 80 percent of adults below age 36 claiming they could lead “healthier” lives. In their eyes, a slim and toned physique boosts better confidence, indicates wellbeing, and serves as proof of self-care.

Unfortunately, the modern way of life provides little time or opportunity to maintain ‘good’ exercise and dietary habits. Most of us are prone to eating quickly, maintaining sedentary lives, sleeping less, and over-consuming calorie-rich foods – all of which contribute to weight gain.

But even though over two-thirds of Americans are overweight, roughly one-third of the population maintain healthy body weight, indicating that it is not an impossible goal. To help speed things along, some individuals resort to diet pills that suppress appetite, speed up metabolism, and prevent fat absorption. 

Diet pills are available in various forms, including soft gels, capsules, and tablets. But just because these drugs can be purchased freely from drugstores across the country, they should not be abused. I cannot stress the importance of following the dosage recommended or prescribed by the manufacturer or your doctor at all times.

In case you’ve made up your mind about consuming weight loss supplements, you might as well go for the best weight loss pills available in the market. I advise you to read up on each of them – their ingredients, benefits, and side effects – to make an informed decision. It’s also a good idea to consult your physician before beginning a specific course.

List of Best Diet Pills for Weight Loss

The weight loss market in America is valued at a whopping $72 billion. Despite a dip in the number of dieters, the market is saturated with more than thousands of different diet pills. This makes it somewhat challenging for people to figure out which are the suitable fat burners for their needs.

Thankfully, I have compiled a list of the ten best weight loss pills that fulfill the body image goals of most dieters. Hope you find it useful!


Manufactured by Wolfson Berg Limited, PhenQ is a high quality, natural dietary supplement. Not only does it promote weight loss, but it also prevents fat production, burns stored fat, and enhances energy levels and mood. While it hasn’t been a market staple as long as some of the other items on this list, I had to include it since it combines several benefits into a single bottle.

The ingredients of this pill are a unique mix of classic fat burners, such as Capsimax Powder and advanced ones like α-Lacys RESET. The latter is a trademarked formula not found in any other dietary supplement that gives this pill an edge over the competition. Consumption decreases body fat by 24 percent, body weight by 44 percent, and improves muscle mass by 8 percent.

Other active ingredients include:

  • Chromium Picolinate
  • L-Carnitine Fumarate
  • Nopal

During my research, I also found that the formula packs a caffeine punch, making PhenQ a solid way to begin your day.

The best part is, all ingredients contained in PhenQ are clinically sanctioned and approved by the FDA. Thus, ingesting these diet pills should ideally help you fit into your dream pair of skinny jeans without worrying about potential health hazards and side effects.

But I did some digging and it turns out each body reacts differently. So, there is a slight possibility you may feel nauseous or experience a mild elevation in heart rate owing to the caffeine content.


Phen375 is a strong fat burner that improves metabolism and the body’s natural ability to digest and burn fat. You feel more energetic after taking this pill, which makes you more active and helps you burn those pesky calories away.

Since its launch in 2009, one million bottles of Phen375 have been sold globally to over 300,000 customers and with good reason. More than six different ingredients in this weight loss pill play a role in your weight loss journey, including:

  • Cayenne Pepper
  • L-Carnitine
  • Dendrobium Nobile Extract
  • Caffeine Anhydrous
  • Citrus Aurantium
  • Coleus Forskolii Root

Phen375 improves metabolic processes and reduces cravings. The natural ingredients offer a much-needed energy boost and slow down the rate of fat cell regeneration. If that’s not all, the pill also has mild antidepressant properties, combating the adverse effects of the slimming phase like loss of energy, strength, exhaustion, and fatigue.

The product is manufactured in FDA-approved labs and no side effects have been detected till now. So, I believe if you follow the instructions regarding dosage and how to take the pill carefully, you should not encounter any health problems.

Burn XT

A popular addition to best weight loss pills lists, The Burn XT is a capsule that burns calories faster, improves fat metabolism, and suppresses the appetite. According to the manufacturer of this supplement, it also boosts energy and improves stamina that comes in handy when you’re building lean muscle during workouts.

Designed to cater to the weight loss requirements of both women and men, Burn XT is the brainchild of the Jacked Factory brand. The pill is a thermogenic fat burner that metabolically stimulates cells to increase energy and heat expenditure. This rise in metabolic activity increases the basal metabolic weight, leading to fat loss.

Burn XT works in multiple ways:

  • It burns body fat
  • Retains muscle
  • Keeps you happy than hungry
  • Makes you feel vigorous and energized
  • Burns extra calories

Thus, it’s no surprise that many dieters choose Burn XT to combat the excess flab. It’s a cutting-edge, potent fat-burner developed from bioavailable ingredients without any dyes or fillers.

Some of the ingredients that go into the making of this drug include:

  • Green Tea leaf extract
  • Bioperine
  • Capsimax extract
  • Caffeine Anhydrous
  • Acetyl L-Carnitine

These are all safe and effective, and you should be fine as long as you follow the instructions regarding administration and dosage from the manufacturer.

As far as side effects are concerned, I went through numerous reviews on this capsule and, other than a few reports of stomach pain it generally seems safe. This might be due to the presence of caffeine, excess doses of which can have side effects like sleeplessness, vomiting, nausea, irritability, nervousness, jitteriness, rapid heartbeat and dizziness.

Skinny Gal

As the name suggests, this is one of the best weight loss pills for the ladies. The 100 percent natural formula is developed by women and contains African Mango, Garcinia Cambogia, CLA, and Raspberry ketones as active ingredients. A great way to shed the excess pounds quickly, these thermogenic pills act as a “Hyper Metabolizer”.

So what makes Rockstar’s Skinny Gal such a hot favorite? Well, for starters, the pill boosts metabolic rates and increases the effects of your exercise and diet efforts. Apart from that, this weight loss pill is 100 percent vegan and vegetarian-friendly!

Skinny Gal works extremely fast when it comes to burning fat and also detoxifies the body. Combined with a little to moderate effort on your part in changing your exercise or diet routine, you should see noticeable results.

Still, despite all the good reviews garnered by this pill, some users complained of fatigue and nausea. I found an online review claiming Skinny Gal helped the user lose several pounds of water weight the initial few days, but she gained it back later. Also, appetite suppression is apparently not one of its strengths.

Apex TX5

Another thermogenic addition in this list of best weight loss pills is the APEX TX5. This is a natural alternative to high potency solutions that offers all the fat-burning benefits without any of the side effects. Manufactured by Intechra Health Inc., this nutraceutical supports weight management when combined with a healthy, balanced diet.

According to the manufacturers, APEX TX5 helps you:

  • Burn fat
  • Lose weight rapidly
  • Feel less fatigued and tired
  • Maintain muscle
  • Retain more energy during workouts

So, pop one of these bad boys and get ready to give it your 100 percent at the gym. You will get plenty of energy to power through your regular exercise routines without any burnout. Your metabolic rate will also undergo a substantial boost, allowing you to shed the excess flab faster.

The active ingredients of this drug, including Theobromine, Acetyl L-Carnitine, and Caffeine are all potent yet safe. Adults can take this pill for its weight management properties. People of different body shapes and sizes will benefit from improved metabolism after regularly having the APEX TX5. Get rid to kiss the stubborn fat from your body goodbye and welcome the perfect beach bod just in time for summer!

CLA 1250

The CLA 1250 by NatureWise is a mainstay in most “best of” weight loss pills compilations and this one’s no exception. Conjugated Linoleic Acid – CLA for short – is a weight loss miracle drug. Why? Because studies found that overweight women lost 9 percent body fat in a year without changing their dietary or lifestyle patterns.

There are plenty of reasons to select CLA 1250 to aid your weight loss efforts:

  • Burns fat instead of muscle
  • Increases energy for better workouts
  • Possesses thermogenic properties
  • Adheres to ISO 17025 standards

No wonder so many bodybuilders, weightlifters, and fitness enthusiasts pick this diet pill to fulfill their fitness goals.

The main ingredient in this potent weight loss solution is premium, standardized safflower oil. Your body needs CLA fatty acid and this drug contains 100 percent natural safflower oil, standardized to a high potency of 80 percent active CLA 1000 mg per 1250 mg softgel.

If you’re wondering about the side effects, my research uncovered a few mild symptoms like nausea, fatigue, stomach upset, and/or diarrhea. However, as long as you limit the dosage to 6 grams a day or as prescribed, you should not experience any long-term negative effects of this drug.

Vintage Burn

The cleverly named Vintage Burn is among the first weight loss supplements to be marketed exclusively towards men. But this keto-friendly diet pill works on both men and women to curb their appetites and reduce their cravings.

The pills aid your fat-burning efforts while maintaining muscle, which is the right way to lose weight. Get the benefits of:

  • Rapid weight loss
  • Improved energy and mood
  • Retention of lean muscle mass
  • 100 percent vegetarian

The ingredients are all-natural and there are zero artificial substances, preservatives or synthetic additives used in the manufacturing of this drug. Some of the notable organic substances include raspberry ketones, Garcinia Cambogia, and Green Tea leaf extract.

Vintage Burn has received lots of positive reviews over the years, bolstering its popularity. The majority of users reported impressive results. But a few complained of side effects found in other thermogenic items, including sleeplessness, vomiting, stomach pain, dizziness, nervousness, heartburn, headaches, and irritability.

This pill has been in the market for over 40 years and it has withstood the test of time to become one of the most trusted weight loss pills in the industry. Manufactured by Old School Labs, the drug works great if you’re seeking a muscle-preserving fat burner.

Most reviews share the same consensus – this pill actually works. I personally find this to be a high-quality item that doesn’t produce any jitters and helps you get your abs back with moderate effort.

Alli Diet Pills

Specially prepared to aid overweight adults in the long and difficult weight loss journey, Alli Diet Pills have been available in the market for over twenty years. People often ask me whether they are still effective, and I’m happy to say that the answer is a resounding yes!

If your BMI, like mine, is higher than 25, you find it easy to pack on the pounds but losing them takes a toll on your mental and physical wellbeing. With the help of Alli Diet Pills, you can:

  • Inhibit up to 25 percent of your body’s fat absorption process.
  • Maintain a balanced weight easily.
  • Lose two to three extra pounds easily for every five pounds lost without the help of the pills.

I found out that this drug is basically an over-the-counter version of orlistat, a prescription pill. So, Alli is meant to be used as part of a weight-loss regimenone that includes a low-fat, low-calorie diet and moderate physical activity.

According to the FDA, Alli diet pills are not responsible for any liver injuries. However, you should notify your doctor at once if you experience any of the following symptoms:

  • Loss of appetite
  • Brown urine
  • Light-colored stool
  • Yellowing of skin or eyes
  • Itching

These GI symptoms show up in just a small fraction of users who start taking Alli, but they are nothing severe. However, if they persist even after a couple of days, they might indicate a different health problem. It is best to consult your physician in these instances.

I should point out that this marks the first item on this list of best weight loss pills that is geared explicitly towards a specific group – the obese – and it performs admirably, as is evident from the testimonies I read from satisfied customers of this dietary supplement going back twenty years.

Considering how obesity affects 39.8 percent of US adults over the age of 20, it’s time to change the ongoing lifestyle and switch to a balanced diet with regular exercise. Once you start taking Alli diet pills, you’ll see a drastic improvement in your body within some time.

Garcinia Cambogia

You’ll find different brands of this pill in the market, but the one I chose specifically for this list is NatureWise’s product. This is a non-stimulating formula – one that’s devoid of any side effects. Not only does it decrease body fat naturally but it even curbs your appetite.

I snooped online a bit and noticed that numerous third parties have already conducted tests on this fat burner’s potency and purity. And the results are overwhelmingly positive! NatureWise’s product contains 500 mg per capsule and is rich in naturally occurring potassium and calcium for improved absorption.

NatureWise’s Garcinia Cambogia is vegan, gluten-free, and non-GMO. It only contains organic ingredients and you won’t experience any adverse effects if you use it to cut down on your body’s excess flab. Given the benefits, it’s easy to see why this product is so popular and flies off the online shelves.

Some of the features of this supplement include:

  • 60 percent standardized HCA
  • 100 percent pure Garcinia cambogia
  • Non-stimulating and natural
  • Reduces fat storage
  • Boosts metabolism
  • Improves serotonin levels and elevates mood
  • Decreases appetite

If you are determined to cut down on your excess body weight, NatureWise’s Garcinia Cambogia can make your journey a lot easier. I found a study claiming how it promotes rapid weight loss.

I couldn’t find reports of any side effects on the Internet. If you stick to the manufacturer’s instructions and check the authenticity of the product during purchase, I think you’ll end up with a great, natural product in your hands. It’s not surprising that the pill is a favorite among many fitness enthusiasts, nutritionists, and personal trainers.

Lean PM Fat Burner

I thought long and hard about the final addition to this list of best weight loss pills, and the logical choice was Lean PM fat burner. What makes this formula unique is the manufacturer’s claims of helping you shed weight during your sleep. Sounds like a dream come true, right?

Well, Lean PM fat burner is great for:

  • Burning fat (obviously)
  • Reducing appetite
  • Improving mood
  • Enhancing sleep quality and energy levels
  • Decreasing weight

There is no caffeine present in this formula, so you can bid symptoms like jitteriness and nervousness goodbye. This is a proprietary blend of organic, herbal ingredients that are guaranteed to help you lose weight, including L-Theanine, Magnesium, Green Tea Extract, Vitamin B6, Bioperine, and Melatonin.

The standout ingredient is, of course, the rich amounts of EGCG or epigallocatechin-3-gallate, which is extracted from green tea. It possesses a host of health benefits, including immunity-boosting properties, stress reduction, cell damage resistance, and reducing cancer risks.

This is a great choice for a weight loss supplement if you’re planning to shape up the easy way. The sleep-promoting solution is quite balanced and you absorb more nutrients in your body.

Frequently Asked Questions

  • What are dietary supplements?

    Dietary supplements are products that have “dietary ingredients” that are aimed at supplementing the human diet. The ingredients include minerals, vitamins, herbs, amino acids, other botanicals, and other substances like concentrates, enzymes, or extracts.

    Dietary supplements, as well as probiotics, that contain potentially good yeasts or bacteria, came in many like capsules, tablets, soft gels, powders, gel caps, or liquids.

  • Do weight loss pills work?

    Alone, diet pills won’t be as effective. Therefore, they should be taken accompanied by regular exercises program and a healthy diet for you to have positive results.

    While not all weight-loss pills work, studies have shown positive weight loss results from using the supplements mentioned above.

  • Are diet pills addictive?

    Abuse and addiction to diet pills can be problematic, especially among teens. The diet pills that contain high amounts of stimulants can make users more susceptible to addiction.

    Again, when a user suffered from eating disorders, they are prone to abusing these pills by thinking that taking higher doses will result in faster weight loss.

  • What happens if I take a lot of diet pills?

    Overdosing on diet pills will potentially increase your blood pressure to quite dangerous levels. When you overdose, you will be risking having a heart attack or a stroke.

  • Are weight loss pills bad for you?

    Note that there are diet pills that mix high quantities of other diuretics and caffeine. These substances can cause weight loss that occurs from you losing water weight.

    Weight loss in this manner is not sustainable because fat-burning did not occur. Instead, you are eliminating water weight as you are dehydrated, and this is not healthy. Fortunately, many diet pills use safe and all-natural ingredients.


People often ask me why they’re not achieving their desired weight loss goals even after beginning the fat burner course. The truth is, getting a toned, fit physique involves a lot more than swallowing a few pills every day.

I have undertaken extensive research and found that the beneficial results of weight loss capsules only emerge if you combine them with regular exercise and a proper diet. On their own, they might fall short of your expectations, or even worse, fail to shed any weight at all.

Also, please note that what worked for someone else may not work for you. You need to play it smart and safe when choosing the best weight loss pill. So, stay positive and begin your new lifestyle regimen to keep those pesky pounds at bay!

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